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Research programme: Dolaflexin antibody-drug conjugates - Merck KGaA/ Mersana Therapeutics

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Drug Profile

Research programme: Dolaflexin antibody-drug conjugates - Merck KGaA/ Mersana Therapeutics

Alternative Names: antibody-drug conjugates- Dolaflexin

Latest Information Update: 12 Mar 2024

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At a glance

  • Originator Mersana Therapeutics
  • Developer Merck KGaA; Mersana Therapeutics
  • Class Drug conjugates; Immunoconjugates
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Unspecified

Most Recent Events

  • 15 Dec 2023 Merck and Mersana Therapeutics terminates their collaboration and commercial license agreement to develop novel immunostimulatory antibody-drug conjugates
  • 26 Sep 2023 Preclinical trials in Unspecified in USA (unspecified route) (Mersana Therapeutics pipeline, September 2023)
  • 28 Mar 2023 Mersana Therapeutics has patent protection for antibody-drug conjugates (ADCs) utilising the Fleximer® polymer in the US

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