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AKV 9

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Drug Profile

AKV 9

Alternative Names: AKV-9; NU 9

Latest Information Update: 14 May 2025

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At a glance

  • Originator Northwestern University
  • Developer AKAVA Therapeutics; Northwestern University
  • Class Antidementias; Cyclohexanes; Neuroprotectants; Small molecules
  • Mechanism of Action Protein aggregation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alzheimer's disease; Amyotrophic lateral sclerosis; Motor neuron disease

Most Recent Events

  • 06 May 2025 Akava Therapeutics plans a phase I trial for Amyotrophic lateral sclerosis (In Volunteers) (PO)
  • 17 Dec 2024 Pharmacodynamics data from a preclinical studies in Amyotrophic lateral sclerosis released by Akava Therapeutics
  • 03 Jul 2023 The US FDA approves IND application for AKV 9 in Amyotrophic lateral sclerosis

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