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HLX 6018

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Drug Profile

HLX 6018

Alternative Names: GARP/TGF-β1 monoclonal antibody - Shanghai Henlius Biotech; HLX-6018

Latest Information Update: 30 Apr 2024

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At a glance

  • Originator Shanghai Henlius Biotech
  • Class Anti-inflammatories; Antifibrotics; Monoclonal antibodies
  • Mechanism of Action LRRC32 protein inhibitors; Transforming growth factor beta type I receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Idiopathic pulmonary fibrosis

Most Recent Events

  • 23 Apr 2024 Phase-I clinical trials in Idiopathic pulmonary fibrosis (In volunteers) in China (IV) (NCT06310746)
  • 23 Apr 2024 Adverse events and pharmacodynamics data from a preclinical studies in Fibrosis released by Shanghai Henlius Biotech
  • 15 Mar 2024 Shanghai Henlius Biotech plans a phase I trial in Idiopathic-pulmonary-fibrosis (In-volunteers) in April 2024 (NCT06310746)

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