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OCU 410 ST

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Drug Profile

OCU 410 ST

Alternative Names: AAV5-hRORA; OCU-410-ST

Latest Information Update: 03 Apr 2024

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At a glance

  • Originator Schepens Eye Research Institute
  • Developer Ocugen
  • Class Eye disorder therapies; Gene therapies
  • Mechanism of Action Gene transference; Nuclear receptor subfamily 1 group F member 1 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Stargardt disease; Retinitis pigmentosa; Cone rod dystrophies
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Stargardt disease
  • Preclinical Cone rod dystrophies; Retinitis pigmentosa

Most Recent Events

  • 01 Apr 2024 Adverse event data from the phase I/II GARDian trial in Stargardt disease released by Ocugen
  • 25 Aug 2023 Phase-I/II clinical trials in Stargardt disease (In children, In adults) in USA (Subretinal) (NCT05956626)
  • 21 Aug 2023 Ocugen plans phase-I/II trial for Stargardt disease by the end of 2023
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