OKI 219
Alternative Names: OKI-219Latest Information Update: 24 Mar 2025
At a glance
- Originator OnKure Therapeutics
- Class Antineoplastics; Small molecules
- Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Phosphotransferase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Breast cancer; Solid tumours
Most Recent Events
- 10 Mar 2025 Adverse events data from the phase Ia/Ib PIKture-01 trial in Solid tumours and Breast cancer released by OnKure Therapeutics
- 10 Dec 2024 Adverse events and pharmacokinetics data from a phase I PIKture-01 trial in Solid tumor was presented at the 47th Annual San Antonio Breast Cancer Symposium (SABCS-2024)
- 10 Dec 2024 Adverse events and pharmacokinetics data from the phase Ia/Ib PIKture-01 trial in Solid tumours and Breast cancer released by OnKure Therapeutics