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Abiraterone acetate/niraparib - Janssen

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Drug Profile

Abiraterone acetate/niraparib - Janssen

Alternative Names: AKEEGA; CJNJ-67652000

Latest Information Update: 13 Jun 2025

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At a glance

  • Originator Janssen
  • Class Androstenols; Antiandrogens; Antineoplastics; Benzamides; Indazoles; Phenanthrenes; Piperidines; Pyridines; Small molecules
  • Mechanism of Action CYP17A1 protein inhibitors; Poly(ADP-ribose) polymerase 2 inhibitors; Poly(ADP-ribose) polymerase-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Prostate cancer

Most Recent Events

  • 03 Jun 2025 Efficacy and adverse event data from a phase III AMPLITUDE trial in Prostate cancer released by Johnson and Johnson
  • 10 Jan 2025 Abiraterone acetate/niraparib is still in phase I development in Prostate-cancer (Hormone refractory, Metastatic disease) in United Kingdom, Ukraine, Sweden, Spain, Poland, Netherlands, Moldova, Georgia, France, Belgium, USA (PO) (NCT04577833)
  • 28 Nov 2024 No recent reports of development identified for phase-I development in Prostate-cancer(Hormone refractory, Metastatic disease) in United Kingdom, Ukraine, Sweden, Spain, Poland, Netherlands, Moldova, Georgia, France, Belgium, USA (PO)

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