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Doxorubicin liposomal - Thermosome

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Drug Profile

Doxorubicin liposomal - Thermosome

Alternative Names: DPPG2-TSL-DOX; THE-001

Latest Information Update: 23 Jun 2023

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At a glance

  • Originator Thermosome
  • Class Anthracyclines; Antineoplastics; Antivirals; Cytostatic antibiotics; Doxorubicins; Hepatoprotectants; Small molecules
  • Mechanism of Action DNA intercalators; Reactive oxygen species stimulants; RNA synthesis inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma
  • New Molecular Entity No

Highest Development Phases

  • Phase I Soft tissue sarcoma
  • Preclinical Bladder cancer; Breast cancer

Most Recent Events

  • 25 May 2023 Preclinical trials in Bladder cancer in Germany (IV), prior to May 2023 (Thermosome pipeline, May 2023)
  • 25 May 2023 Preclinical trials in Breast cancer in Germany (IV), prior to May 2023 (Thermosome pipeline, May 2023)
  • 24 May 2023 Doxorubicin liposomal - Thermosome receives Orphan Drug status for Soft tissue sarcoma in Europe

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