Drug Profile

Eiletoclax - Eilean Therapeutics

Alternative Names: ZE-500134

Latest Information Update: 14 Aug 2025

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At a glance

Originator Eilean Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action Proto-oncogene protein c-bcl-2 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Lymphoma

Most Recent Events

08 Apr 2025 Phase-I clinical trials in Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA (PO) (NCT06708897)
08 Apr 2025 Phase-I clinical trials in Lymphoma (Second-line therapy or greater) in USA (PO) (NCT06708897)
21 May 2024 Eilean Therapeutics initiates a phase I trial (In volunteers) in Australia (PO) (NCT06787131)

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