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Eiletoclax - Eilean Therapeutics

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Drug Profile

Eiletoclax - Eilean Therapeutics

Alternative Names: ZE-500134

Latest Information Update: 29 Jan 2025

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At a glance

  • Originator Eilean Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein c-bcl-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Chronic lymphocytic leukaemia

Most Recent Events

  • 21 May 2024 Eilean Therapeutics initiates a phase I trial (In volunteers) in Australia (PO) (NCT06787131)
  • 09 Dec 2023 Pharmacodynamics and pharmacokinetics data from a preclinical trial in Acute myeloid leukaemia and Chronic lymphocytic leukaemia presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)
  • 31 Oct 2023 Phase-I clinical trials in Acute myeloid leukaemia (unspecified route) (before October 2023) (Eilean Therapeutics pipeline, October 2023)

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