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MHB 018A

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Drug Profile

MHB 018A

Alternative Names: MHB-018A

Latest Information Update: 08 Dec 2025

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At a glance

  • Originator Minghui Pharmaceutical (Shanghai)
  • Class Eye disorder therapies; Immunoglobulin Fc fragments; Recombinant fusion proteins; Single-domain antibodies
  • Mechanism of Action IGF type 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Graves ophthalmopathy

Most Recent Events

  • 03 Dec 2025 Minghui Pharmaceutical (Shanghai) plans a phase III open-label extension trial for Graves ophthalmopathy in China (SC, Injection), in January 2026 (NCT07262476)
  • 22 Jul 2025 Phase-III clinical trials in Graves ophthalmopathy in China (SC) (NCT06989918)
  • 22 Oct 2024 Minghui Pharmaceuticals plans a phase III trial for Graves ophthalmopathy, in August 2025 (SC) (NCT06989918)

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