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AVA NP 695

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Drug Profile

AVA NP 695

Alternative Names: AVA-NP-695

Latest Information Update: 13 Jun 2025

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At a glance

  • Originator Avammune Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 30 May 2023 Avammune Therapeutics has patent pending for "2-amino-s6-substituted thiopurine compounds as inhibitors of the enpp1 protein" in South Korea, China, Australia, Japan, Canada, Brazil, USA, Europian union and Israel
  • 30 May 2023 Avammune Therapeutics publishes a PCT application for "2-amino-s6-substituted thiopurine compounds as inhibitors of the enpp1 protein"

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