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LCB 97

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Drug Profile

LCB 97

Alternative Names: LCB-97; ONO-7429

Latest Information Update: 14 Aug 2026

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At a glance

  • Originator LegoChem Biosciences
  • Developer LigaChem Biosciences; Ono Pharmaceutical
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 31 Jul 2026 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater) in Japan (IV) (jRCT2041260054) (Ono pharma pipeline, July 2026)
  • 10 Oct 2024 LCB 97 licensed to Ono Pharmaceutical in world
  • 14 Apr 2023 Early research in Solid tumours in South Korea (Parenteral) prior to June 2023 (LegoChem Biosciences pipeline, June 2023)

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