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PTX 299

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Drug Profile

PTX 299

Alternative Names: PTX-299

Latest Information Update: 07 May 2026

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At a glance

  • Originator PineTree Therapeutics
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action ErbB receptor degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 29 Apr 2026 AstraZeneca exercises its option to license PTX 299 from Pinetree Therapeutics
  • 23 Jul 2024 AstraZeneca and PineTree Therapeutics enters licensing agreement for the development of PTX 299
  • 23 Jul 2024 AstraZeneca and PineTree Therapeutics plans a clinical trial for Cancer

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