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Estianeptine - Tonix Pharmaceuticals Holding Corp

Drug Profile

Estianeptine - Tonix Pharmaceuticals Holding Corp

Alternative Names: Single (S)-isomer tianeptine - Tonix Pharmaceuticals; TNX-4300

Latest Information Update: 02 Aug 2023

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At a glance

  • Originator Tonix Pharmaceuticals Holding Corp
  • Class Antidementias; Antiparkinsonians; Mood stabilisers; Small molecules; Thiazepines; Tricyclic antidepressants
  • Mechanism of Action Peroxisome proliferator-activated receptor delta agonists; Peroxisome proliferator-activated receptor gamma agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Alzheimer's disease; Bipolar disorders; Major depressive disorder; Parkinson's disease

Most Recent Events

  • 26 Jul 2023 Tonix files patents claiming single (S)-isomer estianeptine and crystalline salt forms of estianeptine that appear well suited to formulation
  • 23 May 2023 Tonix Pharmaceuticals announces intention to submit IND application (Tonix Pharmaceuticals pipeline, May 2023)
  • 23 May 2023 Preclinical trials in Alzheimer's disease in USA (PO) before May 2023
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