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HCB 101

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Drug Profile

HCB 101

Alternative Names: HCB-101; SIRPα-Fc fusion protein - HanchorBio

Latest Information Update: 23 Jun 2025

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At a glance

  • Originator HanchorBio
  • Class Antineoplastics; Immunoglobulin Fc fragments; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action CD47 antigen inhibitors; Phagocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Phase I Non-Hodgkin's lymphoma

Most Recent Events

  • 17 Jun 2025 Interim efficacy data from a phase I trial in Solid tumours released by HanchorBio
  • 13 Mar 2025 Phase-I/II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, Recurrent) in China (IV) (NCT06771622)
  • 14 Jan 2025 FBD Biologics plans a phase I/II trial for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, Recurrent) in January 2025 (NCT06771622)

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