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ASP 2957

Drug Profile

ASP 2957

Alternative Names: ASP-2957; KT-430; MyoAAV3.8-engineered-capsid-myosin-heavy-chain-kinase-7-human-myotubularin; MyoAAV3.8-MHCK7-hMTM1

Latest Information Update: 04 Jun 2026

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At a glance

  • Originator Kate Therapeutics
  • Developer Astellas Pharma; Kate Therapeutics
  • Class Gene therapies
  • Mechanism of Action Gene transference; Myotubularin replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Congenital structural myopathies

Most Recent Events

  • 15 Dec 2025 Phase-I/II clinical trials in Congenital structural myopathies (In neonates, In infants, In children) in USA, Canada (IV) (NCT07052929)
  • 21 Nov 2024 Kate Therapeutics has been acquired by Novartis
  • 08 Jun 2023 KT 430 licensed to Astellas Pharma worldwide for the treatment of Congenital structural myopathies of

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