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AAVB 081

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Drug Profile

AAVB 081

Alternative Names: AAVB-081

Latest Information Update: 16 Dec 2024

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At a glance

  • Originator AAVantgarde Bio
  • Class Eye disorder therapies; Gene therapies
  • Mechanism of Action Gene transference; Myosin VIIa replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Usher syndrome type 1B
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Usher syndrome type 1B

Most Recent Events

  • 09 Dec 2024 Adverse events data from a phase I/II trial in Usher syndrome type 1B released by AAVantgarde Bio
  • 02 Dec 2024 AAVB 081 receives Orphan Drug status for Usher syndrome type 1B in USA
  • 02 Jul 2024 Phase-I/II clinical trials in Usher syndrome type 1B in Italy (Subretinal) (NCT06591793)

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