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MB 109

Drug Profile

MB 109

Alternative Names: MB-101 (IL-13Rα2) + MB-108 oncolytic virus; MB-109; MB101+ MB108

Latest Information Update: 30 Oct 2023

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At a glance

  • Originator City of Hope National Medical Center; Mustang Bio
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Anaplastic astrocytoma; Glioblastoma

Most Recent Events

  • 26 Oct 2023 US FDA accepts IND application for MT-109 in Glioblastoma and Anaplastic astrocytoma
  • 26 Oct 2023 Mustang Bio plans a phase I trial for Glioblastoma and Anaplastic astrocytoma in 2024
  • 22 Jun 2023 Mustang Bio announces intention to submit IND to US FDA for Glioblastoma and Anaplastic astrocytoma in 2023
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