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SKB 410

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Drug Profile

SKB 410

Alternative Names: MK-3120; SKB-410

Latest Information Update: 26 Nov 2025

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At a glance

  • Originator Sichuan Kelun Pharmaceutical Research Institute
  • Developer Merck Sharp & Dohme; Sichuan Kelun Pharmaceutical Research Institute
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Bladder cancer; Solid tumours

Most Recent Events

  • 21 Nov 2025 Phase-I/II clinical trials in Bladder cancer in USA (Intravesicular) (NCT07222488)
  • 18 Nov 2025 Merck Sharp & Dohme plans the phase I/II MK-3475-04D/​KEYMAKER-U04-Substudy 04D, rolling-arm umbrella platform trial for Bladder cancer (Combination therapy, First-line therapy, Late-stage disease, Metastatic disease, Inoperable/unresectable) (IV, Infusion) (NCT07232602)
  • 30 Oct 2025 Merck Sharp & Dohme plans a phase I/II trial for Bladder cancer (Intravesical), in December 2025 (NCT07222488)

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