Lenacapavir pacfosacil - Gilead Sciences
Alternative Names: GS-4182Latest Information Update: 09 Apr 2026
At a glance
- Originator Gilead Sciences
- Class Antiretrovirals
- Mechanism of Action Capsid protein inhibitors
-
Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase II/III HIV-1 infections
Most Recent Events
- 16 Mar 2026 Gilead Sciences terminates phase II/III WONDERS 2 trial in HIV-1 infections (Combination therapy, Treatment-naive) in USA, Spain, South Africa, Romania, Puerto Rico, Portugal, Poland, Germany, Canada (PO) due to sponsor decision (NCT06613685)
- 10 Jun 2025 US FDA places clinical hold on HIV treatment trials of GS 1720 and GS 4182
- 21 Oct 2024 Phase-II/III clinical trials in HIV-1 infections (Combination therapy, Treatment-naive) in USA (PO) (NCT06613685)