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TGW 101

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Drug Profile

TGW 101

Alternative Names: TGW-101

Latest Information Update: 03 Jul 2025

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At a glance

  • Originator Tagworks Pharmaceuticals
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunoglobulin Fv fragments; Immunotoxins; Recombinant proteins
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics, pharmacokinetics and adverse events data from a preclinical trial in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 22 Apr 2025 Phase-I clinical trials in Solid tumours (Late-stage disease) in USA (Parenteral) (NCT06959706)
  • 22 Apr 2025 US FDA approves IND application for TGW 101 in Solid tumours

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