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HCB 301

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Drug Profile

HCB 301

Alternative Names: 2023-3979 Solid Tumors - HanchorBio; HCB-301

Latest Information Update: 11 Nov 2025

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At a glance

  • Originator HanchorBio
  • Class Antibodies; Immunoglobulin Fc fragments; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action CD47 antigen inhibitors; Programmed cell death-1 ligand-1 inhibitors; SIRPA protein inhibitors; Transforming growth factor beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Hodgkin's disease; Solid tumours

Most Recent Events

  • 05 Nov 2025 Regulatory body approves IND application for HCB 301 in USA and China, prior to November 2025
  • 05 Nov 2025 Pharmacodynamics data from preclinical trials in Solid tumours released by HanchorBio
  • 02 Apr 2025 Phase-I clinical trials in Hodgkin's disease (Late-stage disease, Second-line therapy or greater) in China (IV)

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