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TL 118 - Teligene US

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Drug Profile

TL 118 - Teligene US

Alternative Names: TL-118; TL118-Teligene US

Latest Information Update: 29 Sep 2023

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At a glance

  • Originator Teligene US
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Tropomyosin-related kinase antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 24 Aug 2023 Preclinical trials in Solid tumours in USA (PO) prior to August 2023 (NCT06010342)
  • 24 Aug 2023 Teligene US plans a phase II trial for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in unknown location (PO, Capsule) in January 2024 (NCT06010342)
  • 13 Jan 2023 Teligene US has patent granted for substituted pyrazolopyrimidines useful as kinases inhibitors in Finland, Japan, China, Spain, Europe and USA
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