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Fluoroethylnormemantine - ReST Therapeutics

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Drug Profile

Fluoroethylnormemantine - ReST Therapeutics

Alternative Names: FENM - ReST Therapeutics; RST-101

Latest Information Update: 03 Jun 2026

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At a glance

  • Originator ReST Therapeutics
  • Class Adamantanes; Amines; Fluorinated hydrocarbons; Neuroprotectants; Small molecules
  • Mechanism of Action NMDA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Post-traumatic stress disorders

Most Recent Events

  • 28 May 2026 US FDA accepts the IND application for RST 101 for Post-traumatic stress disorder in USA
  • 28 May 2026 ReST Therapeutics plans a first-in-human clinical trial for Post-traumatic stress disorder (In volunteers) in USA (PO)
  • 04 Sep 2024 ReST Therapeutics announces intention to submit our IND Application in Q3 2024 (ReST Therapeutics pipeline; September 2024)

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