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Lidocaine - Orexa

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Drug Profile

Lidocaine - Orexa

Alternative Names: ORE-001

Latest Information Update: 07 Sep 2025

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At a glance

  • Originator Orexa
  • Class Acetanilides; Amines; Class Ib antiarrhythmics; Local anaesthetics; Non-opioid analgesics; Small molecules
  • Mechanism of Action Cell membrane permeability inhibitors; Opioid delta receptor agonists; Opioid receptor agonists; Sodium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Anorexia; Postoperative ileus

Most Recent Events

  • 07 Sep 2025 Orexa plans to initiate a phase II trial for Anorexia nervosa (PO) (CTIS2023-510499-30-00)
  • 24 Jun 2025 Orexa terminates a phase II clinical trials in Postoperative ileus (Prevention) in Germany (PO) due to sponsor decision (NCT05923086) (EudraCT 2022-503113-31-00-IN-002) (CTIS2022-503113-31-01)
  • 17 Feb 2025 Phase-II clinical trials in Anorexia in Netherlands (PO) (CTIS2024-516958-22-00) (EudraCT2024-516958-22-00)

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