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DB 1312

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Drug Profile

DB 1312

Alternative Names: Antibody drug conjugate - DualityBio/BeOne Medicines; BG-C9074; DB-1312

Latest Information Update: 11 Jun 2025

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At a glance

  • Originator Duality Biologics
  • Developer BeOne Medicines; Duality Biologics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 02 Jun 2025 Interim adverse events, efficacy and pharmacokinetics data from a phase-I trial in Solid tumours released by BeOne Medicines
  • 30 Dec 2024 BeiGene in-licenses DB 1312 from Duality Biologics
  • 12 Apr 2024 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in Australia (IV) (NCT06233942)

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