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SPY 130

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SPY 130

Alternative Names: PR-026; SPY-130

Latest Information Update: 14 Mar 2024

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At a glance

  • Originator Paragon Therapeutics
  • Developer Paragon Therapeutics; Spyre Therapeutics
  • Class Anti-inflammatories; Monoclonal antibodies
  • Mechanism of Action Alpha4beta7 integrin antagonists; Interleukin 23 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Inflammatory bowel diseases

Most Recent Events

  • 07 Mar 2024 Spyre Therapeutics plans to initiate combination toxicology studies in 2025
  • 31 Dec 2023 Preclinical trials in Inflammatory bowel diseases in USA (SC)
  • 14 Jul 2023 Early research in Inflammatory bowel diseases in USA (SC) (Paragon Therapeutics pipeline, July 2023) (Spyre Therapeutics website - July 2023)

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