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SPY 120

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Drug Profile

SPY 120

Alternative Names: PR-022 - Spyre Therapeutics; SPY-120

Latest Information Update: 07 Mar 2024

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At a glance

  • Originator Paragon Therapeutics
  • Developer Paragon Therapeutics; Spyre Therapeutics
  • Class Anti-inflammatories; Monoclonal antibodies
  • Mechanism of Action Alpha4beta7 integrin antagonists; Tumour necrosis factor ligand superfamily member 15 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Inflammatory bowel diseases

Most Recent Events

  • 07 Mar 2024 Spyre Therapeutics plans to initiate a clinical studies for SPY120 in 2025
  • 07 Mar 2024 Spyre Therapeutics announces intention to submit IND for Inflammatory bowel diseases in 2025
  • 06 Mar 2024 Preclinical trials in Inflammatory bowel diseases in USA (SC)

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