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Zocilurtatug pelitecan - ZAI Lab

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Drug Profile

Zocilurtatug pelitecan - ZAI Lab

Alternative Names: YL-212; ZL-1310

Latest Information Update: 16 Nov 2025

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At a glance

  • Originator ZAI Lab
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Small cell lung cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Small cell lung cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 11 Nov 2025 Zai Lab plans a phase III trial in Small cell lung cancer (Second line therapy or greater) (Parenteral) (NCT07218146)
  • 31 Oct 2025 Phase-III clinical trials in Small cell lung cancer (Second-line therapy or greater, Monotherapy) (IV) (NCT07218146)
  • 24 Oct 2025 Efficacy and adverse events data from a phase I trial in Small cell lung cancer released by Zai Lab

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