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JSKN 016

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Drug Profile

JSKN 016

Alternative Names: JSKN-016

Latest Information Update: 26 Nov 2025

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At a glance

  • Originator Alphamab Oncology
  • Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Phase I/II HER2 negative breast cancer
  • Phase I Solid tumours

Most Recent Events

  • 26 Nov 2025 Phase-I clinical trials in HER2-negative-breast-cancer (Monotherapy) (IV)
  • 26 Nov 2025 Phase-II clinical trials in Non-small cell lung cancer (Combination therapy) (IV) (Alphamab Oncology pipeline; November 2025) (https://www.alphamabonc.com/en/pipeline/jskn016.html)
  • 26 Nov 2025 Phase-II clinical trials in Non-small cell lung cancer (Monotherapy) (IV)

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