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JSKN 016

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Drug Profile

JSKN 016

Alternative Names: JSKN-016; JSKN-016-HC

Latest Information Update: 11 Aug 2026

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At a glance

  • Originator Alphamab Oncology
  • Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Triple negative breast cancer
  • Phase II Non-small cell lung cancer
  • Phase I/II HER2 negative breast cancer
  • Phase I Solid tumours

Most Recent Events

  • 04 Aug 2026 JSKN 016 licensed to Pathos excluding China, Hong Kong, Macau and Taiwan
  • 04 Aug 2026 Phase-I clinical trials in Solid tumours (Late-stage disease, Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater) in China (SC) (CTR20262241)
  • 02 Jun 2026 Updated adverse event and efficacy data from a phase-I trial in Solid tumours presented at the 62nd Annual Meeting of the American Society of Clinical Oncology 2026 (ASCO-2026)

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