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STI 8591

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Drug Profile

STI 8591

Alternative Names: AC-0939; STI-8591

Latest Information Update: 02 Feb 2024

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At a glance

  • Originator ACEA Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Tropomyosin-related kinase antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia
  • Preclinical Liver cancer

Most Recent Events

  • 02 Feb 2024 Preclinical trials in Liver cancer in China (unspecified route), prior to February 2024 (ACEA Therapeutics pipeline, February 2024)
  • 09 Dec 2023 Pharmacodynamics data from a preclinical trial in Acute myeloid leukemia presented at the 65th American Society of Hematology Annual Meeting and Exposition
  • 08 Dec 2023 Phase-I clinical trials in Acute myeloid leukaemia (Second-line therapy or greater, Late-stage disease) in China (PO) (NCT05947344)

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