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CPO 301

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Drug Profile

CPO 301

Alternative Names: CPO-301; SYS-6010

Latest Information Update: 06 Mar 2026

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At a glance

  • Originator Conjupro Biotherapeutics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates; Immunotherapies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Squamous cell cancer
  • Phase I Solid tumours
  • Clinical Phase Unknown Colorectal cancer; Gastrointestinal cancer

Most Recent Events

  • 04 Mar 2026 CSPC Megalith Biopharmaceutical plans a phase III SYNSTAR03 trial for Non-small cell lung cancer (Second-line therapy or greater, Metastatic disease, Late-stage disease) in March 2026 (IV, Injection)(NCT07442565)
  • 18 Feb 2026 CSPC Megalith Biopharmaceutical plans a phase III trial for Squamous cell cancer (Inoperable/Unresectable, Metastatic disease, Late-stage disease, Second-line therapy or greater, Recurrent, in March 2026 (IV) (NCT07417735)
  • 12 Feb 2026 CSPC Megalith Biopharmaceutical plans a phase III trial for Breast cancer (Recurrent, Inoperable/Unresectable, Metastatic disease, Late-stage disease, Second-line therapy or greater) in April 2026 (IV, Infusion) (NCT07406542)

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