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CPO 301

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Drug Profile

CPO 301

Alternative Names: CPO-301; SYS-6010

Latest Information Update: 04 Feb 2026

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At a glance

  • Originator Conjupro Biotherapeutics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates; Immunotherapies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Squamous cell cancer
  • Phase I Solid tumours
  • Clinical Phase Unknown Colorectal cancer; Gastrointestinal cancer

Most Recent Events

  • 02 Feb 2026 CSPC Megalith Biopharmaceutical plans a phase III SYNSTAR-02 trial for Non-small cell lung cancer (Metastatic diseases, Late-stage diseases, Combination therapy, Second line therapy or greater) in March 2026 (IV) (NCT07376382)
  • 18 Dec 2025 Phase-II clinical trials in Squamous cell cancer (Recurrent, Metastatic disease, Combination therapy) in China (IV) (NCT07254585)
  • 01 Dec 2025 CSPC Megalith Biopharmaceutical plans a phase II trial for Non-small Cell Lung Cancer (Neoadjuvant therapy, Combination therapy) (IV, Infusion) (NCT07256509)

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