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BBI 825

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Drug Profile

BBI 825

Alternative Names: BBI-825

Latest Information Update: 30 Jan 2026

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At a glance

  • Originator Boundless Bio
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Ribonucleotide reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 20 Jan 2026 Boundless Bio terminates a phase-I/II POTENTIATE trial in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) due to strategic portfolio prioritization by the company (NCT05827614)
  • 22 Oct 2025 Pharmacodynamics data from a preclinical study in Solid tumours presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)
  • 25 Jun 2025 Boundless Bio completes the phase I/II STARMAP trial in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA (PO) (NCT06299761)

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