Drug Profile

BBI 825

Alternative Names: BBI-825

Latest Information Update: 20 May 2025

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At a glance

Originator Boundless Bio
Class Antineoplastics; Small molecules
Mechanism of Action Ribonucleotide reductase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

09 May 2025 Pharmacodynamics data from preclinical studies in Solid tumour released by Boundless Bio
25 Apr 2025 Pharmacodynamics data from preclinical studies in Solid tumour released by Boundless Bio
12 Dec 2024 Boundless Bio terminates a phase I/II trial in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA (PO) due to lack of dose-proportional exposure, and the increasing complexity and associated development costs(NCT06299761)

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