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Oruvestat - Vantage Biosciences

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Drug Profile

Oruvestat - Vantage Biosciences

Alternative Names: VX-01

Latest Information Update: 28 Aug 2026

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At a glance

  • Originator Unknown
  • Developer Vantage Biosciences
  • Class Anti-inflammatories; Eye disorder therapies; Small molecules
  • Mechanism of Action AOC3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Diabetic macular oedema; Diabetic retinopathy

Highest Development Phases

  • Phase II Diabetic retinopathy
  • No development reported Diabetic macular oedema

Most Recent Events

  • 28 Aug 2026 No recent reports of development identified for phase-I development in Diabetic-macular-oedema in United Kingdom (PO)
  • 04 Aug 2026 Vantage Biosciences completes enrolment in its phase II trial for Diabetic retinopathy in Malaysia, Hong Kong, South Korea, Australia, USA (PO) (NCT06770933)
  • 11 Feb 2025 Phase-II clinical trials in Diabetic retinopathy in Malaysia, Hong Kong, South Korea, Hong Kong, Australia, USA (PO) (NCT06770933)

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