Drug Profile

CLM 022

Alternative Names: CLM-022

Latest Information Update: 26 Jun 2026

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At a glance

Originator Celloram
Developer Genfit
Class Anti-inflammatories; Hepatoprotectants; Small molecules; Triterpenes
Mechanism of Action Antioxidants; NLRP3 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Inflammatory bowel diseases; Liver disorders

Most Recent Events

11 Nov 2025 Pharmacodynamics data from preclinical studies in Liver disorders presented at the 76th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2025)
11 Nov 2025 Genfit plans to advance CLM 022 in Liver failure
22 Sep 2025 Genfit plans a first-in-human trial in liver disorders in the first half of 2027

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