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CLM 022

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Drug Profile

CLM 022

Alternative Names: CLM-022

Latest Information Update: 04 Jun 2025

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At a glance

  • Originator Celloram
  • Developer Genfit
  • Class Anti-inflammatories; Hepatoprotectants; Small molecules; Triterpenes
  • Mechanism of Action Antioxidants; NLRP3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Inflammatory bowel diseases; Liver disorders

Most Recent Events

  • 04 Jun 2025 Pharmacodynamics data from a preclinical trial in Liver disorders presented at the 75th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2024)
  • 24 Apr 2025 Genfit plans a first-in-human trial in liver disorders as early as end of 2026 or beginning of 2027
  • 24 Apr 2025 Genfit plans a formulation development and first toxicological studies in liver disorders in 2025

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