Drug Profile

JWTCR 001

Alternative Names: JWTCR-001; TCR-MAGE-A4 T-Cells

Latest Information Update: 03 Oct 2025

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At a glance

Originator MediGene AG
Developer JW Therapeutics
Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Phase I Solid tumours

Most Recent Events

18 Sep 2025 bluebird bio is now called Genetix Biotherapeutics
14 Jan 2025 Medigene has patent protection for MAGE-A4-targeted TCR in Japan
05 Dec 2024 Medigene has patent protection for JWTCR 001 in China

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