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NXE 0027477

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Drug Profile

NXE 0027477

Alternative Names: GSK-4381406; HTL-0027477; NXE'477; NXE-0027477

Latest Information Update: 02 Apr 2024

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At a glance

  • Originator Sosei Heptares
  • Developer Nxera Pharma
  • Class Anti-inflammatories; Small molecules
  • Mechanism of Action GPR35 protein agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Inflammatory bowel diseases

Most Recent Events

  • 31 Mar 2024 Sosei Heptares is now called Nxera Pharma
  • 21 Mar 2024 HTL 0027477 (formerly GSK 4381406) is no longer licensed to GSK
  • 21 Mar 2024 Preclinical trials in Inflammatory bowel diseases in United Kingdom (PO) prior to March 2024

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