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SPX 303

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Drug Profile

SPX 303

Alternative Names: SPX-303

Latest Information Update: 03 Apr 2024

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At a glance

  • Originator Sparx Therapeutics
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; LILRB2 protein inhibitors; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 20 Mar 2024 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT06259552)
  • 30 Oct 2023 US FDA approves IND application for SPX 303 in Solid tumours
  • 30 Oct 2023 Sparx Therapeutics plans a phase I trial in solid tumours (Late-stage disease, Second-line therapy or greater) (Parenteral)

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