SPX 303
Alternative Names: SPX-303Latest Information Update: 03 Apr 2024
At a glance
- Originator Sparx Therapeutics
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; LILRB2 protein inhibitors; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 20 Mar 2024 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT06259552)
- 30 Oct 2023 US FDA approves IND application for SPX 303 in Solid tumours
- 30 Oct 2023 Sparx Therapeutics plans a phase I trial in solid tumours (Late-stage disease, Second-line therapy or greater) (Parenteral)