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NC 605

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Drug Profile

NC 605

Alternative Names: NC-605

Latest Information Update: 28 Jul 2025

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At a glance

  • Originator NextCure
  • Class Antibodies
  • Mechanism of Action Siglec-15 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Osteogenesis imperfecta; Spinal cord injuries

Most Recent Events

  • 24 Jul 2025 NextCure plans to file an IND application with the US FDA for Osteogenesis imperfecta in 12 to 18 months
  • 24 Jul 2025 Pharmacodynamics data from a preclinical trial in Osteogenesis imperfecta released by NextCure
  • 19 Nov 2024 Pharmacodynamics data from a preclinical trial in Osteogenesis imperfecta released by NextCure

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