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SAR 449548

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Drug Profile

SAR 449548

Alternative Names: ADEL-Y01; SAR-449548

Latest Information Update: 14 Aug 2026

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At a glance

  • Originator ADEL
  • Developer ADEL; Oscotec
  • Class Antidementias; Monoclonal antibodies
  • Mechanism of Action Tau protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Alzheimer's disease

Most Recent Events

  • 19 Jun 2026 Sanofi plans to initiate clinical trials in Alzheimer's disease
  • 30 Apr 2026 Alzheimer's Disease Expert Lab terminates a phase I trial in Alzheimer's disease in USA (IV) due to a sponsor-led operational transition and strategic decision not to continue the protocol (NCT06247345)
  • 25 Mar 2026 Alzheimer's Disease Expert Lab suspends a phase I trial in Alzheimer's disease in USA (IV) due to the enrollment has been paused due to a sponsor-led operational transition (NCT06247345)

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