Drug Profile

LTG 001

Alternative Names: LTG-001

Latest Information Update: 26 Nov 2025

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At a glance

Originator Latigo Biotherapeutics
Class Non-opioid analgesics; Small molecules
Mechanism of Action Nav1.8 voltage-gated sodium channel inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Postoperative pain
Phase I Acute pain

Most Recent Events

01 Oct 2025 Latigo Biotherapeutics plans a phase II trial for Pain in Denmark (PO, Tablet), in October 2025 (CTIS2025-522755-26-01; LTG-001-015)
08 Aug 2025 Latigo Biotherapeutics completes a phase II trial in Postoperative pain in USA (PO) (NCT06774625)
24 Jul 2025 Latigo Biotherapeutics initiates enrolment in a phase-II trial for Postoperative pain in USA (PO) (NCT07102459)

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