Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

BMS 986458

Next Previous
Drug Profile

BMS 986458

Alternative Names: BCL6 LDD; BMS-986458

Latest Information Update: 13 Mar 2026

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Bristol-Myers Squibb
  • Class Amines; Antineoplastics; Chlorinated hydrocarbons; Indazoles; Indoles; Ketones; Piperidines; Pyrimidines; Small molecules
  • Mechanism of Action BCL6 protein degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Non-Hodgkin's lymphoma

Most Recent Events

  • 13 Mar 2026 Chemical structure information added.
  • 08 Dec 2025 Efficacy and adverse events data from phase I/II clinical trials in Non-Hodgkin's lymphoma released by Bristol Myers Squibb
  • 06 Dec 2025 Efficacy, adverse event and pharmacodynamics data from phase-I/II clinical trials in Non-Hodgkin's lymphoma presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top