Drug Profile

BMS 986458

Alternative Names: BCL6 LDD; BMS-986458

Latest Information Update: 10 Dec 2025

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At a glance

Originator Bristol-Myers Squibb
Class Antineoplastics; Small molecules
Mechanism of Action Undefined mechanism

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Non-Hodgkin's lymphoma

Most Recent Events

08 Dec 2025 Efficacy and adverse events data from phase I/II clinical trials in Non-Hodgkin's lymphoma released by Bristol Myers Squibb
12 Jun 2025 Efficacy and adverse events data from a phase I/II trial in Non-Hodgkin's lymphoma released by Bristol-Myers Squibb
07 Dec 2024 Pharmacodynamics data from a preclinical trial in Non-Hodgkin's lymphoma presented at the 66^th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)

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