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BMS 986458

Drug Profile

BMS 986458

Alternative Names: BCL6 LDD; BMS-986458

Latest Information Update: 18 Jun 2025

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At a glance

  • Originator Bristol-Myers Squibb
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Non-Hodgkin's lymphoma

Most Recent Events

  • 12 Jun 2025 Efficacy and adverse events data from a phase I/II trial in Non-Hodgkin's lymphoma released by Bristol-Myers Squibb
  • 07 Dec 2024 Pharmacodynamics data from a preclinical trial in Non-Hodgkin's lymphoma presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
  • 20 Sep 2024 Phase-I/II clinical trials in Non-Hodgkin's lymphoma (Combination therapy, Second-line therapy or greater) in USA, France, Germany, Netherlands, Spain, Switzerland (PO) (NCT06090539)

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