Drug Profile

AGA 2115

Alternative Names: AGA-2115

Latest Information Update: 20 Jan 2026

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At a glance

Originator Angitia Biopharmaceuticals
Class Bispecific antibodies
Mechanism of Action DKK1 protein inhibitors; SOST protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

Yes - Osteogenesis imperfecta
New Molecular Entity Yes

Highest Development Phases

Phase II Osteogenesis imperfecta

Most Recent Events

12 Dec 2025 Phase-II clinical trials in Osteogenesis imperfecta (In adults) in USA (SC) (NCT07062588)
08 Sep 2025 Pharmacodynamics data from preclinical studies in Osteogenesis imperfecta released by Angitia Biopharmaceuticals
05 Sep 2025 Pharmacodynamics data from a preclinical trial in Osteogenesis imperfecta presented at the Annual Meeting of the American Society for Bone and Mineral Research 2025 (ASBMR-2025)

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