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YOLT 101

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Drug Profile

YOLT 101

Alternative Names: SAL-061; YOLT-101

Latest Information Update: 19 Mar 2026

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At a glance

  • Originator YolTech Therapeutics
  • Developer Shenzhen Salubris Pharmaceuticals; YolTech Therapeutics
  • Class Antihyperlipidaemics; Gene therapies
  • Mechanism of Action Gene transference; PCSK9 protein expression inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Hypercholesterolaemia

Most Recent Events

  • 18 Mar 2026 Shenzhen Salubris Pharmaceuticals expect to initiate the extension stage of its phase I clinical trial in patients with Heterozygous familial hypercholesterolemia (HeFH) in 2027
  • 13 Nov 2025 Phase-I clinical trials in Hypercholesterolaemia in China (IV) (CTR20254123)
  • 30 Sep 2025 Updated efficacy data from a phase 0 trial in Hypercholesterolemia released by Shenzhen Salubris Pharmaceuticals

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