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YOLT 203

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Drug Profile

YOLT 203

Alternative Names: YOLT-203

Latest Information Update: 26 Aug 2026

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At a glance

  • Originator YolTech Therapeutics
  • Class Gene therapies; Uricosurics
  • Mechanism of Action Gene expression modulators; Glycolate oxidase expression inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Primary hyperoxaluria type 1
  • New Molecular Entity No

Highest Development Phases

  • Phase II Primary hyperoxaluria type 1
  • Preclinical Hyperuricaemia

Most Recent Events

  • 20 Aug 2026 Phase-I clinical trials in Primary hyperoxaluria type 1 (In adolescents, In children) in China (IV) (NCT07776626)
  • 12 Aug 2026 Phase-II clinical trials in Primary hyperoxaluria type 1 (In adults, In adolescents, In children, In the elderly) in USA (IV) (NCT07587021)
  • 14 May 2026 YolTech Therapeutics plans a phase II trial for Primary-hyperoxaluria in June 2026 (IV) (NCT07587021)

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