Drug Profile

TGM 148

Alternative Names: ETX-148; TGM-148

Latest Information Update: 08 Oct 2025

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At a glance

Originator e-Therapeutics
Developer Tangram Therapeutics
Class Amides; Amino sugars; Antihaemorrhagics; Drug conjugates; Small interfering RNA
Mechanism of Action RNA interference

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

08 Oct 2025 Preclinical trials in Blood coagulation disorders in United Kingdom (Parenteral)
01 Oct 2025 Tangram Therapeutics plans a clinical trial for Blood coagulation disorders in 2026
01 Oct 2025 e-Therapeutics plans to file an IND application for Blood coagulation disorders in mid 2026

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