Drug Profile

TGM 148

Alternative Names: ETX-148; TGM-148

Latest Information Update: 06 Nov 2025

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At a glance

Originator e-Therapeutics
Developer Tangram Therapeutics
Class Amides; Amino sugars; Antihaemorrhagics; Drug conjugates; Small interfering RNA
Mechanism of Action RNA interference

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Blood coagulation disorders

Most Recent Events

06 Nov 2025 Adverse events and pharmacodynamics data from preclinical trials in Blood coagulation disorders released by Tangram Therapeutics (Tangram Therapeutics pipeline, November 2025)
08 Oct 2025 Preclinical trials in Blood coagulation disorders in United Kingdom (SC)
01 Oct 2025 Tangram Therapeutics plans a clinical trial for Blood coagulation disorders in 2026

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