Drug Profile

SIM 0505

Alternative Names: SCR-9359; SIM-0505

Latest Information Update: 30 Jul 2026

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At a glance

Originator Simcere Zaiming
Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
Mechanism of Action DNA topoisomerase I inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Solid tumours

Most Recent Events

02 Jun 2026 Efficacy, adverse event and pharmacokinetic data from a phase I trial in Solid tumours presented at the 62^ndAnnual Meeting of the American Society of Clinical Oncology (ASCO-2026)
01 Jun 2026 Adverse events and efficacy data from a phase I trial in Solid tumours released by NextCure
04 May 2026 NextCure plans a registrational trial

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